Asparaginasa

Resumen

Alternativas con registro en Colombia

• Hidroxicarbamida
• Mitotane · costo anual estimado $ 98.359.105
• Pegaspargasa
• Arsenico Trioxido · costo anual estimado $ 1.706.778.690
• Anagrelida · costo anual estimado $ 73.836.580
• Eribulina
• Venetoclax · costo anual estimado $ 259.178.835

Estudios clínicos principales

• An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)
  Fase 2/3 · 2019 · 229 participantes · Jazz Pharmaceuticals · NCT04145531 · PubMed 36108304
• Trybeca-1: Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC
  Fase 3 · 2018 · 512 participantes · ERYtech Pharma · NCT03665441
• Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma
  Fase 3 · 2000 · 393 participantes · Children's Oncology Group · NCT00004228 · PubMed 22994934 · PubMed 22488718
• Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia
  Fase 3 · 2006 · 1.070 participantes · Children's Oncology Group · NCT00372593 · PubMed 25092781

Enfermedades relacionadas

• Cáncer (todos)
• Leucemias
• Linfomas

Fuentes

• Etiqueta FDA (DailyMed): Rylaze
• EMA: Spectrila