Sugammadex

Resumen

Alternativas con registro en Colombia

• Edetatos
• Pralidoxima
• Tiosulfato
• Protamina
• Naloxona
• Metiltioninio Cloruro
• Acetilcisteina
• Flumazenil
• Idarucizumab

Estudios clínicos principales

• Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)
  Fase 3 · 2011 · 1.198 participantes · Merck Sharp & Dohme LLC · NCT01422304 · PubMed 25208233
• Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)
  Fase 3 · 2010 · 308 participantes · Merck Sharp & Dohme LLC · NCT00825812 · PubMed 25187755
• Comparison of Sugammadex (Org 25969) With Neostigmine as Reversal Agents for Rocuronium or Vecuronium at Reappearance of T2 (P05960)
  Fase 3 · 2005 · 198 participantes · Merck Sharp & Dohme LLC · NCT00451217 · PubMed 19713265
• Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (1
  Fase 3 · 2005 · 182 participantes · Merck Sharp & Dohme LLC · NCT00473694 · PubMed 20809967 · PubMed 18946293

Fuentes

• Etiqueta FDA (DailyMed): SUGAMMADEX SODIUM
• EMA: Sugammadex Mylan
• EMA: Sugammadex Amomed